Patients with chronic obstructive pulmonary disease (COPD) report improved symptoms and health status when they use a hand-held respiratory device called the Lung Flute®, according to a new study by the University at Buffalo. Usually caused by smoking, COPD, which includes chronic bronchitis and emphysema, is the third leading cause of death in the U.S. The Lung Flute, manufactured by Medical Acoustics, (Buffalo), uses sound waves to break up mucus in the lungs. The device allows patients to clear lung mucus simply by blowing into the hand-held respiratory device, which produces a low frequency acoustic wave.

Published on Sept. 23 in Clinical and Translational Medicine, the 26-week study demonstrates that patients using the Lung Flute experience less difficulty breathing and less coughing and sputum production than a control group, which saw no change in COPD symptoms.

"This study confirms that the Lung Flute improves symptoms and health status in COPD patients, decreasing the impact of the disease on patients and improving their quality of life," says Sanjay Sethi, MD, principal author of the study and professor and chief, division of pulmonary, critical care and sleep medicine in the Department of Medicine, UB School of Medicine and Biomedical Sciences.

The device is approved by the Food and Drug Administration (FDA) to treat COPD and other lung diseases characterized by retained secretions and congestion. It also is approved by FDA to obtain deep lung sputum samples for "laboratory analysis and pathologic examination."

Colleagues of Sethi's in the UB medical school are now studying the Lung Flute for use in improving symptoms in asthma. The device is also being investigated for diagnostic use in tuberculosis and lung cancer.

The study followed 69 patients with COPD for six months; it was conducted at the Veterans Affairs Western New York Healthcare System (Buffalo VA) by researchers at the UB medical school.