经典表达：

I have some personal business that I need to take care of.

我有点私事要处理。

举一反三：

I got some family issues that I need to take a day off.

我有些家庭问题要解决，需要请一天假。

I have a doctor's appointment.

我预约了医生。

I have to go to my son's school tomorrow.

明天我得去一趟儿子的学校。

I need to attend a wedding next Friday.

下周五我要参加婚礼。

I need tomorrow off to attend a funeral.

明天我要请假参加葬礼。