“意见相左”，意思是“想法不同、意见不合”，“相左”表示“不一致”。可以翻译为“conflict with each other”或“disagree in opinion”。或用“not see eye to eye”表示，意思是“to not agree，to not share a position or opinion with someone”。

例句：

首相在这个问题上与他意见相左。

The Prime Minister didn't see eye to eye with him on this issue.