在英语代词中， few 与 little 作形容词用，都表示“几乎没有”，相当于一个否定词。它们具体的区别有以下几个方面：
1、few 后面跟复数可数名词。例如：
There are few books in his room.
There are few students in his class.

2、little 后面跟单数不可数名词。例如：
He has few friends.
他没有几个朋友。
They has little money.
他们没有什么钱。

3、a few 与 a little 都表示肯定的意思，指“有一点，有一些”。
a few 后加可数名词复数。例如：
I'm going to buy a few bananas.
a little 后加不可数名词单数。
I can speak only a little Chinese.

4、a little 与 little 也可以用作副词， 表示“有点”“稍稍” 表示“很少”.例如：
---Can you speak English?
----Yes, but only a little.
This book is a little more difficult than that one.（可修饰形容词比较级）
She slept little last night.
昨天晚上，她没有怎么睡觉。

5、a few / a little 为肯定含义，还有一点；few / little　为否定含义，没有多少了。例如：
He has a few friends.　他有几个朋友。
He has few friends.　他几乎没有朋友。
We still have a little time. 我们还有点时间。
There is little time left.几乎没剩下什么时间了。

6、我们来看看这个例句：
Although he 's wealthy，he spends___ on clothes.
A. little　B. few　C. a little　D. a few
答案：A. spend所指的是钱，不可数，只能用little或 a little. 本句为although引导的让步状语从句，由句意知后句为否定含义，因此应用little表示几乎不。

7、固定搭配：only a few (=few）　not a few (=many）　quite a few (=many) many a (=many)
Many books were sold.
卖出了许多书。